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DA-1726 shows 68% liver fat reduction and 13.5% weight loss in Phase 1 trial for liver-related diseases

Market News
05 Nov 2026, 15:55 WIB
PRNewsWire
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Bullish
DA-1726 shows 68% liver fat reduction and 13.5% weight loss in Phase 1 trial for liver-related diseases

MetaVia announced positive interim Phase 1 results for DA-1726, a dual GLP-1 and glucagon receptor agonist, showing a 68% placebo-adjusted liver fat reduction and 13.5% weight loss after 16 weeks in obese adults. The drug also improved HbA1c levels and reduced visceral and subcutaneous fat while preserving lean muscle. These results support advancing DA-1726 into Phase 2 trials targeting metabolic and alcohol-associated liver diseases, with a 48-week study planned for late 2027. No new serious gastrointestinal side effects were reported after week 9, indicating good tolerability.

MetaVia's DA-1726 interim data shows a 68% liver fat reduction. For readers following health stocks, here is Pluang's market snapshot as of Nov 05, 2026 19:42 WIB: out of 150 US health stocks, 87 rose and 56 fell. Notable moves include IOVA at USD 9.13 (+4.94%), ALNY at USD 168.00 (+4.30%), and OSCR at USD 33.80 (-3.95%).

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