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Darovasertib combo trial meets primary endpoint, IDEAYA plans NDA filing in H2 2026 with strong cash position.

Company Fundamentals
05 May 2026
PRNewsWire
View Source
Bullish
pluang ai news

IDEAYA Biosciences announced positive topline results from the Phase 2/3 OptimUM-02 trial of darovasertib combined with crizotinib for first-line HLA*A2-negative metastatic uveal melanoma, showing a 58% reduction in disease progression risk and improved progression-free survival. The company plans to submit a New Drug Application (NDA) to the FDA in the second half of 2026, aiming for accelerated approval under the Real-Time Oncology Review program. Additional clinical updates for other pipeline candidates are expected in H2 2026, and IDEAYA maintains a strong cash reserve of approximately $973 million, supporting operations into 2030.

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USDT stablecoin use rises in developing countries amid inflation and currency issues

USDT stablecoin use rises in developing countries amid inflation and currency issues

Tether CEO Paolo Ardoino highlighted growing reliance on the USDT stablecoin in countries like Venezuela, Argentina, Bolivia, and Turkey due to inflation, currency depreciation, and limited access to physical dollars. These economies use USDT for dom...

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Bullish
4 hours ago
Upbit adds KRW trading for Lighter's LIT token with initial order restrictions starting Aug 24.

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Upbit will launch a South Korean won (KRW) trading market for Lighter's LIT token on August 24 at 1:00 pm KST. Initially, buy orders will be restricted for about five minutes and only limit orders will be allowed for the first two hours to prevent di...

Market News
Bullish
4 hours ago
US spot Bitcoin ETFs see biggest weekly inflow in 10 months, nearing $2B as Bitcoin nears $80K

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US spot Bitcoin ETFs attracted nearly $1.92 billion in net inflows over the week ending August 22, marking their strongest weekly inflow since October 2025. This surge coincided with Bitcoin's price rally of 18% to 25%, testing levels near $80,000. B...

Market News
Bullish
4 hours ago
Crypto networks use varied consensus methods to secure transactions and finalize blocks.

Crypto networks use varied consensus methods to secure transactions and finalize blocks.

Different major cryptocurrencies use distinct consensus algorithms to validate transactions and secure their blockchains. Bitcoin pioneered Nakamoto Consensus, relying on proof-of-work mining and cumulative computational effort to confirm transaction...

Protocol Fundamentals
Neutral
4 hours ago
Sezzle up 88% in 2026 as Klarna falls 50%, reflecting profit gap in buy now, pay later sector

Sezzle up 88% in 2026 as Klarna falls 50%, reflecting profit gap in buy now, pay later sector

In 2026, buy now, pay later companies Sezzle and Klarna showed contrasting stock performances, with Sezzle rising 88% and Klarna dropping 50%. Sezzle's stronger profitability, with an adjusted EPS of $5.25 projected for 2026 and a price-to-earnings r...

Analyst Insights
Neutral
4 hours ago
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