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NorthStrive's EL-32 shows lean mass benefits with semaglutide in preclinical study, plans further trials.

Market News
05 Nov 2026, 14:31 WIB
GlobeNewsWire
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Bullish
NorthStrive's EL-32 shows lean mass benefits with semaglutide in preclinical study, plans further trials.

NorthStrive Biosciences completed a preclinical study of EL-32, an engineered probiotic aimed at preserving muscle during GLP-1 weight loss therapy with semaglutide. The study in obese mice found that high-dose EL-32 combined with semaglutide led to greater lean mass and improved glucose response compared to semaglutide alone, though benefits were dose-specific and not consistently additive. EL-32 alone showed limited effects. NorthStrive plans a follow-up study using lower semaglutide doses to better assess muscle preservation, with results expected in early 2027. This research targets the unmet need for therapies that maintain muscle during obesity treatment with GLP-1 drugs.

NorthStrive Biosciences' EL-32 preclinical study on muscle preservation during semaglutide therapy is the focus here. For readers following the health sector, here is Pluang's market snapshot as of Nov 05, 2026 19:01 WIB: Of 150 priced health-sector US stocks, 94 rose and 48 fell. Notable movers include BDX at USD 194.84 with a 6.86% decline and 100% sell order activity, IOVA at USD 9.20 gaining 5.75% with a balanced buy-sell order split, and ALMS at USD 6.20 down 5.34%.

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