Opus Genetics has finished dosing the higher-dose Cohort 2 in its Phase 1/2 trial of OPGx-BEST1, a gene therapy for BEST1-related inherited retinal diseases like Best vitelliform macular dystrophy and autosomal recessive bestrophinopathy. Cohort 2 enrolled 11 participants at a dose three times higher than Cohort 1, which showed promising safety and vision improvements. Topline three-month data from Cohort 2 is expected in Q1 2027, with potential Phase 3 dosing planned for the second half of 2027. This progress marks a key step toward developing the first treatment addressing the genetic cause of these rare retinal diseases.
Opus Genetics' gene therapy trial progress is presented here with Pluang's Health sector market data as of Nov 05, 2026 19:01 WIB. Of 150 priced Health-sector US stocks tradable on Pluang, 94 rose and 48 fell today. Notable movers include OSCR at USD 36.95 with a 1-day change of +5.00%, ADPT at USD 27.99 up +4.79%, and BKD at USD 10.69 down -4.47%.
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