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Sotagliflozin reduces blood clot formation and heart muscle workload in hypertrophic cardiomyopathy, new study shows

Market News
09 Nov 2026, 15:30 WIB
GlobeNewsWire
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Bullish
Sotagliflozin reduces blood clot formation and heart muscle workload in hypertrophic cardiomyopathy, new study shows

Lexicon Pharmaceuticals announced new research showing sotagliflozin, a dual SGLT1/2 inhibitor, significantly reduces blood clot formation under arterial and venous conditions and directly lowers myocardial work in hypertrophic cardiomyopathy (HCM) heart tissue. These findings, presented at the 2026 American Heart Association Scientific Sessions, suggest sotagliflozin's potential benefits beyond kidney and metabolic effects, supporting its ongoing Phase 3 SONATA-HCM trial. Topline results from this trial are expected in Q1 2027, potentially offering a new treatment option for HCM patients.

Sotagliflozin's cardiovascular effects are highlighted alongside Pluang's Health-sector market data. For readers following health stocks, here is Pluang's market snapshot as of Nov 09, 2026 19:41 WIB: Out of 150 priced US health-sector stocks, 121 rose and 18 fell. Notable movers include CTXR at USD 0.54 with a -2.98% change and a typical hold time of 19 days, LQDA at USD 45.67 with a +2.86% change and a 4-day hold time, and HIMS at USD 25.29 with a -2.73% change and a 24-day hold time.

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