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New combo therapy shows promise in tough metastatic breast cancer cases with high response rates

Company Fundamentals
09 Nov 2026, 19:00 WIB
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Bullish
New combo therapy shows promise in tough metastatic breast cancer cases with high response rates

Marengo Therapeutics presented interim Phase 2 results from the STARt-002 trial combining invikafusp alfa, a selective T-cell agonist, with sacituzumab govitecan in metastatic triple-negative and HR-positive/HER2-negative breast cancer. The trial showed reductions in tumor lesions in 71% of patients and confirmed complete responses in both cancer subtypes, including durable responses beyond one year. This novel immune therapy combo demonstrated manageable safety and potential to improve outcomes in patients with limited treatment options. Further development is planned to expand its use across broader cancer populations.

Marengo Therapeutics' interim Phase 2 results provide context for readers interested in innovative cancer therapies. For readers following the health sector, here is Pluang's market snapshot as of Nov 09, 2026 18:41 WIB: out of 150 priced US health stocks, 108 rose and 26 fell. Notable movers include TG Therapeutics Inc (TGTX) at USD 63.00 with a 1-day change of +5.31%, Guardant Health Inc. (GH) at USD 157.76 with +4.57%, and ClearPoint Neuro Inc (CLPT) at USD 8.99 with +4.53%.

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