Crispr Therapeutics AG vs Johnson Controls International PLC — how do they compare? Crispr Therapeutics AG trades at $50.98 (market cap $4.97B), while Johnson Controls International PLC trades at $141.98 (market cap $88.61B). The key difference: Johnson Controls International PLC is far larger — about 17.8× Crispr Therapeutics AG's market cap, and Johnson Controls International PLC pays a 1.1% dividend while Crispr Therapeutics AG pays none. Which is the better fit depends on your goals.
| CRSP | JCI | |
|---|---|---|
Market Cap | $4.97B | $88.61B |
Sector | Health | Industrials |
52-Week High | $76.78 | $148.21 |
52-Week Low | $44.34 | $103.24 |
Enterprise Value | $3.32B | $97.44B |
Dividend Yield | — | 1.1% |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
Johnson Controls International (JCI) trades at $143.93, up 0.78% on the day, with a bullish technical outlook and strong analyst support. The stock has consistently beaten earnings estimates in recent quarters, with Q2 2026 EPS expected at $1.33. Revenue for 2025 reached $23.60 billion, with net income surging to $3.29 billion, reflecting a robust profit margin of 13.94%. Recent corporate actions include a $0.40 dividend payment scheduled for July 2026, and positive news flow highlights growth in smart home and building efficiency markets.
JCI presents a favorable investment case driven by earnings momentum, solid profitability, and a unanimous analyst buy consensus with a $158.29 price target. Key risks include elevated valuation multiples (P/E of 43.67) and rising debt-to-asset ratios, which could pressure returns if growth slows. The stock's proximity to its 52-week high suggests limited near-term upside, but operational execution and sector tailwinds support a constructive outlook for patient investors.
Trailing returns across standard periods
Latest headlines on both assets
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →Johnson Controls manufactures, installs, and services HVAC systems, building management systems and controls, industrial refrigeration systems, and fire and security solutions. Commercial HVAC accounts for about 40% of sales, fire and security also represents 40% of sales, and residential HVAC, industrial refrigeration, and other solutions account for the remaining 20% of revenue. In fiscal 2021, Johnson Controls generated over $23.5 billion in revenue.
Read more on JCI →