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Spyre Therapeutics Inc. Common Stock (SYRE) Stock Price Today

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Aura AI Summary

SYRE trades at $80.45, down 6.34% over 24 hours, with technical indicators showing neutral momentum near key support at $79. The clinical-stage biotech shows no revenue but maintains strong analyst support (92% buy rating) with a $119.89 consensus target. Recent positive SPY003 phase II ulcerative colitis data (Zacks, 2026-09-09) and a $350 million public offering (GlobeNewsWire, 2026-10-05) provide catalysts, though financials reflect pre-revenue challenges with a -197.71% net margin.
Investment outlook balances high-risk, high-reward potential. The robust pipeline in inflammatory bowel disease offers substantial upside if clinical successes continue, but the absence of revenue, negative cash flow from operations, and reliance on financing pose significant risks. Near-term price action will hinge on Q3 2026 earnings and further clinical updates.
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Key Stats

  • Market Cap
    $7.52B
  • Volume
    1,441,031
  • Sector
    Health
  • 52W High
    $108.92
  • 52W Low
    $22.18
  • Typical Hold Time
    0 Days
  • Enterprise Value
    $6.52B
  • Div Yield
    -
  • Trading Activity
    0% Sell | 100% Buy
$78.63
52W Low: $22.18
10 Nov 2025
52W High: $108.92
19 Aug 2026

Track Spyre Therapeutics Inc. Common Stock (SYRE) stock price today on Pluang, updated in real time with live charts and market data. Over the past 52 weeks, Spyre Therapeutics Inc. Common Stock has traded between a low of $22.18 and a high of $108.92, highlighting its annual price range. Buy and sell Spyre Therapeutics Inc. Common Stock shares on Pluang with fractional shares and real-time market data — safe and OJK-regulated.

About Spyre Therapeutics Inc. Common Stock

Spyre Therapeutics develops extended half-life antibody therapies for inflammatory bowel disease, including ulcerative colitis and Crohn's disease. Its pipeline targets pathways such as α4β7, TL1A, and IL-23 with antibodies engineered for infrequent subcutaneous dosing and potential combination use.


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Key Stats

  • Market Cap
    $7.52B
  • Volume
    1,441,031
  • Sector
    Health
  • 52W High
    $108.92
  • 52W Low
    $22.18
  • Typical Hold Time
    0 Days
  • Enterprise Value
    $6.52B
  • Div Yield
    -
  • Trading Activity
    0% Sell | 100% Buy
$78.63
52W Low: $22.18
10 Nov 2025
52W High: $108.92
19 Aug 2026

Track Spyre Therapeutics Inc. Common Stock (SYRE) stock price today on Pluang, updated in real time with live charts and market data. Over the past 52 weeks, Spyre Therapeutics Inc. Common Stock has traded between a low of $22.18 and a high of $108.92, highlighting its annual price range. Buy and sell Spyre Therapeutics Inc. Common Stock shares on Pluang with fractional shares and real-time market data — safe and OJK-regulated.

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