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Scribe Therapeutics shows long-lasting cholesterol and lipoprotein(a) reduction in preclinical trials

Market News
04 Nov 2026, 15:00 WIB
GlobeNewsWire
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Bullish
Scribe Therapeutics shows long-lasting cholesterol and lipoprotein(a) reduction in preclinical trials

Scribe Therapeutics announced new preclinical data at the American Heart Association 2026 Scientific Sessions demonstrating that their lead therapy STX-1150 provides persistent LDL cholesterol control for at least two years after a single dose in primates. Additionally, their gene editing therapy STX-1200 showed robust and durable reduction of lipoprotein(a), a major genetic risk factor for cardiovascular disease, in preclinical models. These advances highlight Scribe's potential to offer long-term treatments for heart disease risk factors using CRISPR-based technologies. The company is currently conducting a Phase 1 trial for STX-1150 and plans further development of STX-1200.

Scribe Therapeutics' gene editing and epigenetic silencing therapies are the focus, with Pluang's Health-sector snapshot providing market context. Among 150 priced US health stocks on Pluang, 121 rose and 23 fell as of Nov 04, 2026 19:41 WIB. Notably, Charles River Laboratories Intl. Inc (CRL) dropped 6.21% to USD 330.01 with a typical hold time of 35 days, contrasting with Canopy Growth Corp (CGC) which gained 6.13% to USD 0.75 and saw 100% buy orders and a 40-day hold time, while Novo Nordisk A/S (NVO) rose 5.92% to USD 42.57 with 90% buy orders and a notably longer hold time of 118 days.

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