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Final Phase 3 trial data shows GAVRETO improves outcomes in RET fusion-positive NSCLC; olutasidenib shows promise in AML.

Market News
21 May 2026
PRNewsWire
View Source
Bullish
Final Phase 3 trial data shows GAVRETO improves outcomes in RET fusion-positive NSCLC; olutasidenib shows promise in AML.

Rigel Pharmaceuticals announced that final Phase 3 trial data for GAVRETO (pralsetinib) as a first-line treatment for RET fusion-positive non-small cell lung cancer (NSCLC) will be presented at ASCO 2026, showing improved progression-free survival and response rates over standard care. Additionally, data from Phase 1/2 trials of pralsetinib in RET-altered thyroid cancer and real-world evidence supporting REZLIDHIA (olutasidenib) for relapsed/refractory IDH1-mutated acute myeloid leukemia (AML) were presented. These findings highlight the clinical relevance of Rigel's oncology portfolio and suggest olutasidenib may be an effective post-venetoclax therapy for AML patients. The presentations at ASCO and EHA 2026 will further inform treatment strategies for these difficult-to-treat cancers.

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Rocket Lab secures largest-ever commercial Electron rocket deal, boosting launch backlog past 100.

Rocket Lab secures largest-ever commercial Electron rocket deal, boosting launch backlog past 100.

Rocket Lab has signed the biggest commercial deal in its history for its Electron rocket launches. This milestone deal significantly increases the company's launch backlog, which now exceeds 100 missions. The expanded backlog highlights strong demand...

Market News
Neutral
2 hours ago
SEC proposes rule allowing advisers to hold Bitcoin directly if no qualified custodian is available

SEC proposes rule allowing advisers to hold Bitcoin directly if no qualified custodian is available

The U.S. Securities and Exchange Commission (SEC) is planning a rule change that would permit registered investment advisers to hold Bitcoin directly, but only if no qualified custodian can hold the asset for them. This conditional exception does not...

Market News
Neutral
4 hours ago
Bitcoin stalls below $87,100 as profit-taking rises, testing support at $83,000 for recovery continuation.

Bitcoin stalls below $87,100 as profit-taking rises, testing support at $83,000 for recovery continuation.

Bitcoin failed to break the $87,100 resistance and dropped nearly 4% to around $83,800, though it held above the $83,000 support zone. Short-term holders have increased profit-taking, with realized profits rising to $1.05 billion, adding selling pres...

Market News
Neutral
4 hours ago
NEAR blocked $50M stolen from Bitget but lost $3.8M in its own hack amid a 182% monthly price surge.

NEAR blocked $50M stolen from Bitget but lost $3.8M in its own hack amid a 182% monthly price surge.

NEAR Protocol's cross-chain service stopped over $50 million in stolen funds from the Bitget hack but suffered a $3.8 million exploit two days later due to a smart contract bug. Despite this, NEAR's token surged 182% over the past month, though it fa...

Market News
Bearish
4 hours ago
Ondo's tokenized stock platform hits $1.26B TVL with $28B trading volume, ONDO token steady near $0.49.

Ondo's tokenized stock platform hits $1.26B TVL with $28B trading volume, ONDO token steady near $0.49.

Ondo's stock platform reached a record $1.26 billion in total value locked (TVL), supporting over 450 tokenized stocks and ETFs, with cumulative trading volume surpassing $28 billion. These figures indicate strong product adoption but do not directly...

Protocol Fundamentals
Bullish
4 hours ago
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