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Pralsetinib shows 53% response rate in RET fusion-positive tumors, with strong results in lung and thyroid cancers.

Market News
19 Oct 2026
PRNewsWire
View Source
Bullish
Pralsetinib shows 53% response rate in RET fusion-positive tumors, with strong results in lung and thyroid cancers.

Rigel Pharmaceuticals announced that pooled data from two trials, ARROW and TAPISTRY, show pralsetinib achieves a 53% overall response rate in patients with RET fusion-positive solid tumors, including lung and thyroid cancers. The drug demonstrated durable effectiveness, especially in first-line treatment for RET fusion-positive non-small cell lung cancer (NSCLC), with improved patient quality of life. These findings support pralsetinib's potential as a tumor-agnostic therapy and reinforce its role as a first-line treatment option for RET fusion-positive cancers. Further clinical data will be presented at the ESMO Congress 2026.

The news on Rigel Pharmaceuticals' pralsetinib data is presented with Pluang's Health sector market context. Of 150 priced Health-sector US stocks on Pluang, 68 rose and 54 fell today. Notable movers include Heron Therapeutics Inc (HRTX) at USD 0.37 with a 2.49% increase, Revolution Medicines Inc. (RVMD) at USD 181.96 up 2.25%, and Arrowhead Pharmaceuticals Inc. (ARWR) at USD 56.94 rising 1.86%, as of Oct 19, 2026 18:43 WIB.

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