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PepGen shares double on positive Phase 2 results for DM1 treatment PGN-EDODM1, but clinical hold remains.

Market News
11 Nov 2026, 23:39 WIB
Seeking Alpha
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Bullish
PepGen shares double on positive Phase 2 results for DM1 treatment PGN-EDODM1, but clinical hold remains.

PepGen Inc. stock surged over 100% following positive Phase 2 top-line results for its DM1 treatment PGN-EDODM1, which showed a 46.5% mean splicing correction and functional improvements with good safety at 10 mg/kg over four doses. Despite these promising outcomes, a U.S. clinical hold is still in place, and the small patient sample size (six treated) calls for caution. Investors await data from a higher dose cohort and further regulatory clarity before considering PepGen a safer investment due to ongoing risks and funding needs.

PepGen's recent clinical data is notable context for readers. For those tracking the health sector, 87 of 150 US health stocks on Pluang rose while 61 fell as of Nov 12, 2026 04:11 WIB. Key movers included DNA at USD 10.35 with a 13.82% decline, BFLY at USD 7.23 gaining 11.06%, and BNGO at USD 1.10 down 10.57%.

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