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Ionis cuts 2026 TRYNGOLZA sales forecast by 50%, shares drop sharply.

Market News
10 Nov 2026, 00:35 WIB
PRNewsWire
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Bearish
Ionis cuts 2026 TRYNGOLZA sales forecast by 50%, shares drop sharply.

Ionis Pharmaceuticals lowered its full-year 2026 sales guidance for its drug TRYNGOLZA from $100-$110 million to about $50 million, citing slower-than-expected market adoption. The drug had generated $32 million in sales in the first half of 2026 but is now expected to see a more gradual launch. This downgrade caused Ionis' stock price to fall sharply. Investors who suffered losses are being encouraged to submit information for a potential securities law investigation into whether the company made misleading statements about TRYNGOLZA's sales prospects.

Ionis Pharmaceuticals' stock price dropped sharply by 21.36% on Pluang as of Nov 10, 2026 05:21 WIB, trading at USD 31.00. This decline contrasts with the typical hold time of 10 days on the platform, indicating a swift reaction from investors. Despite the sell-off, all current Pluang orders remain buy orders, showing continued interest in the stock even after the downgrade.

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