Investment
Features
FeesSafety
Academy
More
Pluang+

Novartis shares plunge 12.5% after two Phase 3 drug trials fail primary goals

Market News
09 Sep 2026
PRNewsWire
View Source
Bearish
Novartis shares plunge 12.5% after two Phase 3 drug trials fail primary goals

Novartis shares dropped over 12.5% after its Phase 3 HARBOR trial for del-desiran and Phase 3 HORIZON trial for pelacarsen both failed to meet primary endpoints. These failures mean the drugs did not show significant benefits over placebo for their targeted conditions, impacting investor confidence. A securities law investigation has been launched to examine if Novartis made misleading statements about these drug programs. Investors who suffered losses are encouraged to review their options with legal counsel.

More News (NVS)

Amgen shares drop 10% after Novartis fails cholesterol drug trial, despite Amgen's own cancer trial success.

Amgen shares drop 10% after Novartis fails cholesterol drug trial, despite Amgen's own cancer trial success.

Novartis' failed cholesterol drug trial for pelacarsen caused a sharp 14% drop in its stock and dragged down the entire Lp(a) drug class, hitting Amgen hardest with a 10% decline despite Amgen's positive Phase 3 lung cancer trial results announced th...

Market News
Bearish
1 day ago
Novartis shares drop 10% after del-desiran fails Phase 3 trial for myotonic dystrophy

Novartis shares drop 10% after del-desiran fails Phase 3 trial for myotonic dystrophy

Novartis shares fell up to 10% after its drug del-desiran failed to meet the primary endpoint in the Phase 3 HARBOR study for myotonic dystrophy type 1, showing no significant improvement over placebo. This setback follows another recent late-stage t...

Market News
Bearish
1 day ago
Novartis shares drop after late-stage drug trial failures, but long-term growth outlook remains intact

Novartis shares drop after late-stage drug trial failures, but long-term growth outlook remains intact

Novartis shares fell sharply following the failure of its late-stage drug candidates pelacarsen and del-desiran in phase 3 trials, which impacts the company’s near-term growth prospects. Despite these setbacks, Novartis reaffirmed its revenue growth ...

Market News
Bearish
1 day ago
Novartis' drug pelacarsen fails to reduce heart risks despite lowering harmful cholesterol Lp(a).

Novartis' drug pelacarsen fails to reduce heart risks despite lowering harmful cholesterol Lp(a).

Novartis announced that its drug pelacarsen, designed to lower the harmful cholesterol Lp(a), failed to significantly reduce cardiovascular events in a late-stage trial. This setback raises doubts about the effectiveness of targeting Lp(a) to prevent...

Market News
Bearish
1 day ago
banner-footerbanner-footer

Invest & Trade with
#1 Award-Winning Investment Super App