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Oncolytics Biotech presents trial data on pelareorep for advanced colorectal cancer at ESMO 2026

Market News
20 Oct 2026
GlobeNewsWire
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Bullish
Oncolytics Biotech presents trial data on pelareorep for advanced colorectal cancer at ESMO 2026

Oncolytics Biotech announced the presentation of their REO 033 trial-in-progress at the ESMO Congress 2026, evaluating pelareorep combined with FOLFIRI and bevacizumab for second-line treatment of RAS-mutant, microsatellite-stable metastatic colorectal cancer. This randomized study aims to confirm promising results from a previous trial (REO 022) that showed pelareorep doubled progression-free survival compared to standard care. The trial's primary endpoint is objective response rate, with secondary endpoints including overall survival and safety. Positive FDA interactions may lead to an expanded pivotal study and potential accelerated approval, highlighting pelareorep's potential to improve treatment options in a challenging market segment.

Oncolytics Biotech's REO 033 trial progress in colorectal cancer offers context for health sector activity on Pluang. For readers following health stocks, here is Pluang's market snapshot as of Oct 20, 2026 19:43 WIB: out of 150 priced US health-sector stocks, 89 rose and 58 fell. Notable movers include CTXR at USD 0.45 with a +5.19% change and a typical hold time of 18 days, ENVB at USD 1.34 down -4.96% with 100% sell order activity, and MMED at USD 17.17 down -3.49% with an 11-day hold time.

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