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Oculis completes patient randomization in trial for precision treatment of TNFR1-mediated dry eye disease

Market News
19 Oct 2026
Na
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Bullish
Oculis completes patient randomization in trial for precision treatment of TNFR1-mediated dry eye disease

Oculis Holding AG has completed patient randomization in its PREDICT-1 clinical trial testing Licaminlimab, a precision medicine targeting TNFR1-mediated dry eye disease (DED). Two-thirds of the 176 enrolled patients carry a genetic variant linked to better treatment response. This trial aims to confirm earlier positive phase 2 results showing significant symptom improvement. Topline results are expected by the end of 2026, potentially offering the first targeted therapy for over 1.5 million moderate to severe DED patients in the US with this genetic profile.

Oculis Holding AG's PREDICT-1 trial on Licaminlimab targets a genetic variant found in two-thirds of enrolled patients. For readers following health-sector stocks, here is Pluang's market snapshot as of Oct 19, 2026 13:11 WIB: out of 150 priced US health stocks, 79 rose and 65 fell. Notable movers include Acadia Healthcare Company Inc (ACHC) at USD 29.98 with a -5.34% change and a typical hold time of 8 days, Dyne Therapeutics Inc. (DYN) at USD 14.25 with a -5.25% change and a 3-day hold time, and Davita Inc (DVA) at USD 190.05 with a +5.17% change and a 115-day hold time.

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