Neurocrine Biosciences has initiated a Phase 1 clinical trial to test NBIP-'2118, a new drug targeting the CRF 2 receptor for obesity treatment. This investigational therapy aims to reduce fat while preserving or increasing lean muscle mass, addressing a key limitation of current weight loss drugs. The trial will assess safety and tolerability in healthy and overweight adults, with initial results expected in 2027. Neurocrine is also developing combination therapies to enhance weight loss effects while maintaining muscle preservation.
VYKAT XR (diazoxide choline) treatment demonstrated significant and lasting improvements in hyperphagia and behavioral symptoms in individuals with Prader-Willi syndrome (PWS) for up to three years. Participants who resumed VYKAT XR after a 16-week w...
Neurocrine Biosciences reported that CRENESSITY (crinecerfont) significantly improved hormone levels and reduced glucocorticoid doses in patients with classic congenital adrenal hyperplasia (CAH) due to 11β-hydroxylase deficiency, a rare form of CAH....
Neurocrine Biosciences announced two-year Phase 3 data from the CAHtalyst Pediatric study showing that CRENESSITY (crinecerfont) treatment slows bone age progression and improves predicted adult height in children with classic congenital adrenal hype...
Neurocrine Biosciences announced that two-year data from their Phase 3 CAHtalyst Adult study shows CRENESSITY (crinecerfont) improves cardiometabolic outcomes like insulin resistance, body weight, and bone health in adults with classic congenital adr...
