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Needham raises Vaxcyte price target after strong Phase 3 trial of VAX-31 vaccine

Analyst Insights
05 Oct 2026
Alex Lavoie
View Source
Bullish
Needham raises Vaxcyte price target after strong Phase 3 trial of VAX-31 vaccine

Investment firm Needham increased its price target for Vaxcyte to $122 from $110 following positive Phase 3 trial results for Vaxcyte's VAX-31 pneumococcal vaccine. The vaccine met all primary endpoints in the OPUS-1 trial, showing noninferiority to competitors Pfizer and Merck's vaccines and stronger responses against some strains. This success highlights a major opportunity in the adult pneumococcal vaccine market, potentially worth $3-6 billion. Vaxcyte shares surged 57% after the announcement, signaling strong investor confidence.

Vaxcyte's recent Phase 3 trial success comes as 61 out of 100 health-sector US stocks tradable on Pluang rose today. For readers following health stocks, here is Pluang's market snapshot as of Oct 06, 2026 03:02 WIB: Cytokinetics Inc (CYTK) fell 4.59% to USD 62.59 with a typical hold time of 19 days, 10X Genomics Inc (TXG) rose 4.53% to USD 97.74 with 73% buy order activity and a typical hold time of 93 days, and Danaher Corporation (DHR) dropped 4.47% to USD 211.68 with 72% buy order activity and a typical hold time of 69 days.

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