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Maze Therapeutics completes Phase 2 enrollment for kidney disease drug, expects key data in early 2027

Company Fundamentals
09 Nov 2026, 23:05 WIB
GlobeNewsWire
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Bullish
Maze Therapeutics completes Phase 2 enrollment for kidney disease drug, expects key data in early 2027

Maze Therapeutics announced completion of enrollment in its Phase 2 HORIZON trial for MZE829, a drug targeting APOL1-mediated kidney disease, exceeding patient targets. Interim data showed promising reductions in proteinuria, with full results expected in early 2027 to guide a pivotal trial planned for mid-2027. The company is also advancing MZE782 in Phase 2 trials for phenylketonuria and chronic kidney disease, with topline data expected in 2027 and a new trial planned for H1 2027. Maze reported a strong cash position of $477 million supporting operations through 2029, despite a net loss of $48 million in Q3 2026 due to increased R&D and administrative expenses.

Maze Therapeutics' Q3 2026 results provide context for health sector investors. For readers following health stocks, here is Pluang's market snapshot as of Nov 10, 2026 04:11 WIB: Out of 150 health-sector US stocks, 125 rose and 23 fell today. Notable movers include IBRX at USD 7.11 with a -17.66% change and 96% buy orders, HIMS at USD 21.66 down -16.69% with 100% buy orders, and ARWR at USD 49.30 down -15.23%.

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