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Fulcrum Therapeutics stock plunges 51% after halting sickle cell drug due to FDA safety concerns

Market News
24 Aug 2026
Newsfile Corp
View Source
Bearish
pluang ai news

Fulcrum Therapeutics announced the discontinuation of its sickle cell disease drug, pociredir, after the FDA raised serious safety concerns linked to a high rate of secondary blood cancers observed with a similar drug. This led to no viable regulatory path for further development, causing the company's stock to drop 51% in one day. Kaplan Fox & Kilsheimer LLP is now investigating potential securities violations related to this event, inviting affected investors to come forward. This development highlights significant regulatory risks in drug development for rare diseases and may impact investor confidence in the company.

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