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New dual-antigen immunotherapy shows strong PSA reductions in advanced prostate cancer Phase 1 trial

Company Fundamentals
08 Nov 2026, 18:00 WIB
PRNewsWire
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Bullish
New dual-antigen immunotherapy shows strong PSA reductions in advanced prostate cancer Phase 1 trial

Johnson & Johnson announced promising Phase 1 results for a novel immunotherapy combining pasritamig and JNJ-9401, targeting two prostate cancer proteins to activate T cells. In the trial, 73% of patients saw PSA levels drop by at least 50%, with nearly half achieving reductions of 90% or more, and no severe treatment-related side effects reported. This dual-antigen approach could offer a new outpatient treatment option for metastatic castration-resistant prostate cancer, a condition with limited therapies and poor prognosis. The combination is now advancing to a larger Phase 3 study to confirm its benefits.

Johnson & Johnson shares are trading near their 52-week high, priced at USD 276.22 as of Nov 08, 2026 23:02 WIB, just below the peak of USD 278.43. The stock has gained 1.43% in the past day, reflecting steady investor interest. On Pluang, buying and selling activity is nearly balanced with 51% of orders to buy and 49% to sell, indicating cautious optimism around the health sector giant amid its promising immunotherapy news.

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