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IDEAYA nominates IDE101, a novel dual CDK inhibitor targeting CDKN2A-deficient tumors, aiming for FDA filing in H1 2027.

Market News
15 Nov 2026, 22:00 WIB
PRNewsWire
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Bullish
IDEAYA nominates IDE101, a novel dual CDK inhibitor targeting CDKN2A-deficient tumors, aiming for FDA filing in H1 2027.

IDEAYA Biosciences announced IDE101 as a new development candidate designed to treat tumors with CDKN2A deficiency, common in 10-15% of solid tumors including 70% of pancreatic cancers. IDE101 is a first-in-class dual cyclin-dependent kinase inhibitor showing promising preclinical activity alone and combined with RAS and PRMT5 inhibitors. The company plans to file an Investigational New Drug (IND) application with the FDA in the first half of 2027 after completing ongoing preclinical studies. IDEAYA aims to improve treatment efficacy by targeting tumor suppressor loss alongside oncogenic drivers in these cancers.

IDEAYA Biosciences' new development candidate IDE101 is introduced amid a Health sector where 71 of 150 US stocks rose and 77 fell on the day. For readers following Health stocks, here is Pluang's market snapshot as of Nov 16, 2026 00:01 WIB: HNGE traded at USD 115.39 with a 1-day change of -4.63% and a typical hold time of 12 days; RXRX was at USD 3.19, down 4.35%, with a typical hold time of 23 days and Pluang order activity showing 0% Sell / 100% Buy; BNGO stood at USD 1.00, down 3.85%, with a typical hold time of 52 days.

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