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HCW Biologics unveils innovative T-Cell Engager HCW11-018b for solid tumors, advancing toward clinical trials in 2027

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06 Nov 2026, 16:15 WIB
GlobeNewsWire
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Bullish
HCW Biologics unveils innovative T-Cell Engager HCW11-018b for solid tumors, advancing toward clinical trials in 2027

HCW Biologics presented its lead T-Cell Engager candidate, HCW11-018b, at the 41st Society for Immunotherapy of Cancer meeting, highlighting its unique ability to convert immunologically "cold" tumors into "hot" ones by promoting immune cell infiltration and tertiary lymphoid structure formation. This multivalent molecule targets solid tumors by combining T-cell activation with immunosuppression reduction, showing promising preclinical results including tumor shrinkage and metastasis reduction. The company received FDA guidance for IND submission and plans to start first-in-human trials in early 2027, supported by ongoing GMP manufacturing preparations.

HCW Biologics' lead T-Cell Engager candidate is highlighted here with Pluang's health sector market context as of Nov 06, 2026 20:42 WIB: Among 150 priced health-sector US stocks tradable on Pluang, 51 rose and 94 fell today. Notable movers include Amphastar Pharmaceuticals Inc (AMPH) at USD 29.45, up 6.47% with a typical hold time of 18 days; Cassava Sciences Inc (FLNA) at USD 0.48, up 6.21% with 79% buy order activity and a typical hold time of 39 days; and Erasca Inc. (ERAS) at USD 13.77, up 3.77% with a typical hold time of 4 days.

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