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Phase 3 trial shows Retevmo cuts recurrence risk by 83% in early-stage RET fusion-positive lung cancer.

Company Fundamentals
31 May 2026
PRNewsWire
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Bullish
Phase 3 trial shows Retevmo cuts recurrence risk by 83% in early-stage RET fusion-positive lung cancer.

Eli Lilly announced that the Phase 3 LIBRETTO-432 trial of Retevmo (selpercatinib) significantly improved event-free survival by reducing the risk of recurrence or death by 83% compared to placebo in early-stage RET fusion-positive non-small cell lung cancer patients. This is the first proven targeted adjuvant therapy for this patient group, highlighting the need for comprehensive biomarker testing at diagnosis. The results, to be published in the New England Journal of Medicine and presented at the 2026 ASCO Annual Meeting, may change clinical practice by establishing Retevmo as a new standard of care after surgery or radiation.

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FDA approves Jaypirca for first-line treatment of untreated chronic lymphocytic leukemia without 17p deletion

FDA approves Jaypirca for first-line treatment of untreated chronic lymphocytic leukemia without 17p deletion

The FDA has approved Eli Lilly's Jaypirca (pirtobrutinib) for use as a first-line treatment in adult patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) without the 17p deletion. This approval is ...

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Eli Lilly's revenue jumps 47.7%, eyeing $2 trillion valuation with new drug pipeline boost.

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Eli Lilly's new obesity drug shows stronger weight loss than Novo Nordisk's, raising market competition.

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Foundayo cuts predicted 10-year type 2 diabetes risk by up to 57% and cardiovascular risk by 18% in obese adults.

Foundayo cuts predicted 10-year type 2 diabetes risk by up to 57% and cardiovascular risk by 18% in obese adults.

Eli Lilly's Foundayo (orforglipron) showed in post-hoc analyses of the ATTAIN-1 trial a significant reduction in predicted 10-year risks of type 2 diabetes and cardiovascular disease among adults with obesity or overweight with related health issues....

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