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Xilio Therapeutics starts Phase 1/2 trial for cancer drug XTX501, plans data in Q4 2027

Company Fundamentals
10 Nov 2026, 14:30 WIB
GlobeNewsWire
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Bullish
Xilio Therapeutics starts Phase 1/2 trial for cancer drug XTX501, plans data in Q4 2027

Xilio Therapeutics initiated a Phase 1/2 clinical trial for XTX501, a novel PD-1/masked IL-2 bispecific antibody targeting metastatic non-small cell lung cancer and other solid tumors. The drug aims to improve immune response while reducing side effects common to IL-2 therapies. Xilio also advanced two other masked T cell engager programs targeting gastrointestinal and prostate cancers, with IND applications planned for late 2027. Financially, the company reported a net loss of $5.9 million in Q3 2026 but has $122.2 million in cash, sufficient to fund operations into early 2028.

Xilio Therapeutics' Q3 2026 financial results and pipeline updates provide context for readers. For those following the health sector, here is Pluang's market snapshot as of Nov 10, 2026 18:42 WIB: out of 150 priced US health stocks, 85 rose and 56 fell. Among notable movers, BioNano Genomics Inc (BNGO) rose 1.72% to USD 1.18 with a typical hold time of 53 days and 100% sell order activity, while Revvity Inc (RVTY) increased 1.53% to USD 163.18 with a much shorter hold time of 14 days and also 100% sell orders. LifeStance Health Group Inc (LFST) gained 1.44% to USD 14.81 with a 12-day typical hold time.

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