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SYX-5219 shows safety and immune benefits in Phase 1a trial for atopic dermatitis treatment

Company Fundamentals
13 May 2026, 18:00 WIB
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SYX-5219 shows safety and immune benefits in Phase 1a trial for atopic dermatitis treatment

Sitryx Therapeutics announced positive Phase 1a trial results for SYX-5219, an oral PKM2 modulator targeting atopic dermatitis. The trial in healthy volunteers showed the drug was safe, well tolerated, and demonstrated immune system modulation by reducing a key inflammation biomarker. This supports SYX-5219's potential as a disease-modifying oral therapy for atopic dermatitis. A Phase 1b trial in patients with severe atopic dermatitis is ongoing, with data expected by the end of 2026.

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