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City Therapeutics doses first patient in Phase 1 trial for Stargardt disease RNAi therapy CITY-RBP4

Company Fundamentals
10 Nov 2026, 14:00 WIB
GlobeNewsWire
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Bullish
City Therapeutics doses first patient in Phase 1 trial for Stargardt disease RNAi therapy CITY-RBP4

City Therapeutics has dosed the first participant in its Phase 1 clinical trial of CITY-RBP4, an RNA interference therapy targeting Stargardt disease, a genetic condition causing vision loss. CITY-RBP4 aims to reduce retinol-binding protein 4 (RBP4) to slow retinal damage by limiting vitamin A delivery to the eye. The trial will assess safety and drug effects, with initial data expected by mid-2027. This marks City Therapeutics' second program in clinical testing, advancing their pipeline of RNAi treatments for serious diseases.

City Therapeutics' recent dosing of the first participant in its Phase 1 trial for CITY-RBP4 is noted here alongside Pluang's health sector market snapshot. Of 150 priced health-sector US stocks tradable on Pluang, 85 rose and 56 fell as of Nov 10, 2026 18:42 WIB. Notable movers include FLNA at USD 0.53 with a 7.80% increase and a typical hold time of 39 days, CGC at USD 0.65 up 4.37%, and ABCL at USD 12.96 rising 3.68%, with Pluang order activity heavily weighted to selling for all three.

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