Cabaletta Bio announced Phase 1/2 clinical data for rese-cel, a CAR T cell therapy targeting autoimmune diseases, showing durable benefits without immunomodulators across dermatomyositis, lupus nephritis, and systemic sclerosis patients. All dermatomyositis patients maintained moderate-to-major improvement at one year, lupus nephritis patients achieved remission off immunomodulators, and systemic sclerosis patients showed lung function improvement. The therapy demonstrated a favorable safety profile with mostly mild side effects. Cabaletta plans to report registrational trial results in 2027 and submit regulatory applications in 2028, aiming to offer a one-time immune reset treatment for autoimmune diseases.
Cabaletta Bio's new clinical data on rese-cel provides context for health innovation, alongside Pluang's health sector snapshot as of Nov 08, 2026 22:02 WIB: Among 150 priced US health stocks, 88 rose and 62 fell. TransMedics Group Inc (TMDX) surged 27.92% to USD 88.24 with a typical hold time of 24 days and 67% buy orders, contrasting with Brookdale Senior Living Inc. (BKD) which dropped 16.65% to USD 9.01 and Inovio Pharmaceuticals Inc (INO) down 16.21% to USD 1.22, with INO held typically for 41 days and 70% sell orders.
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