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Bolt Biotherapeutics acquires Prana Therapies, raises $120M to advance PRA-216 in Phase 2 trials for inflammatory diseases

Company Fundamentals
12 Nov 2026, 23:05 WIB
GlobeNewsWire
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Bullish
Bolt Biotherapeutics acquires Prana Therapies, raises $120M to advance PRA-216 in Phase 2 trials for inflammatory diseases

Bolt Biotherapeutics completed its acquisition of Prana Therapies and raised $120 million in private financing, making Prana's pipeline the company's primary focus. Their lead drug, PRA-216, a bispecific antibody targeting IL-4Rα/TSLP, is now in Phase 2 trials for asthma, atopic dermatitis, COPD, and soon eosinophilic esophagitis, with initial data expected in Q2 2027. The acquisition and financing provide Bolt with the capital to advance multiple clinical and preclinical milestones through 2028. This marks a strategic shift to develop next-generation multispecific antibody therapies with convenient dosing schedules.

Bolt Biotherapeutics' recent acquisition and financing news come as Pluang's Health sector shows broad declines, with only 23 of 150 US stocks rising as of Nov 13, 2026 04:11 WIB. For readers following health stocks, here is Pluang's market snapshot: ClearPoint Neuro Inc (CLPT) fell 7.74% to USD 8.46 with 100% sell orders, Nuwellis Inc (NUWE) dropped 7.59% to USD 5.11 also with 100% sell orders, and Moderna, Inc. (MRNA) declined 7.13% to USD 230.95 with a 58% sell order activity and typical hold time of 58 days.

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