Compare Twist Bioscience Corp (TWST) vs Energy Select Sector SPDR Fund (XLE) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Twist Bioscience Corp vs Energy Select Sector SPDR Fund — how do they compare? Twist Bioscience Corp trades at $125.52 (market cap $8.42B), while Energy Select Sector SPDR Fund trades at $65.48. The key difference: Energy Select Sector SPDR Fund is trading nearer its 52-week high, Twist Bioscience Corp nearer its low. Which is the better fit depends on your goals.
| TWST | XLE | |
|---|---|---|
Market Cap | $8.42B | — |
Sector | Health | — |
52-Week High | $153.10 | $65.31 |
52-Week Low | $24.16 | $42.61 |
Enterprise Value | $8.35B | — |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Twist Bioscience (TWST) trades at $128.06, up 2.68% today, but remains below the analyst consensus price target of $106.14. The stock shows mixed technical signals with bearish overall momentum but bullish moving averages. Fundamentally, the company continues to report losses with a net income margin of -31.66% despite 23% revenue growth in Q3 2026. Recent news highlights AI-driven optimism and institutional buying interest.
TWST presents a high-risk growth story with strong analyst support (79% buy ratings) but persistent profitability challenges. The stock's valuation appears stretched with P/S of 18.09 and P/B of 18.89. Key catalysts include AI drug discovery partnerships and path to EBITDA breakeven, while risks include cash burn and competitive pressures in biotech.
XLE trades at $64.78, up 1.12% with strong bullish technical signals from moving averages. The ETF benefits from oil price strength above $100/barrel and geopolitical tensions in the Middle East. Recent performance shows XLE gained 7.4% in August, leading sector ETFs. Technical indicators show RSI at 78.15 suggests overbought conditions while ADX indicates strong trend momentum.
Outlook remains positive given energy sector tailwinds from supply constraints and winter demand, though elevated oil prices create both opportunity and volatility risk. The ETF's concentrated holdings in major energy companies provide leveraged exposure to crude price movements, with valuations reflecting long-term oil prices below current spot levels.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Twist Bioscience Corp
Twist Bioscience Corp is a synthetic biology company. It develops a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's DNA synthesis platform utilizes a proprietary semiconductor-based synthetic DNA manufacturing process that synthesizes DNA on silicon instead of on traditional well plastic plates to enable the production of high-quality synthetic DNA faster and affordable as well as overcomes inefficiencies. Powering cost-effective, rapid high-throughput synthesis, it enables researchers to rapidly realize opportunities ahead. Geographically, it derives a majority of revenue from the United States.
Read more on TWST →About Energy Select Sector SPDR Fund
In seeking to track the performance of the index, the fund employs a replication strategy. It generally invests substantially all, but at least 95%, of its total assets in the securities comprising the index. The index includes companies that have been identified as energy companies by the GICS®, including securities of companies from the following industries: oil, gas and consumable fuels; and energy equipment and services. It is non-diversified.
Read more on XLE →
