Tempus AI vs Vanguard Total Stock Market Index Fund ETF — how do they compare? Tempus AI trades at $70.06 (market cap $12.58B), while Vanguard Total Stock Market Index Fund ETF trades at $381.75 (market cap $2.30T). The key difference: Vanguard Total Stock Market Index Fund ETF is far larger — about 182.8× Tempus AI's market cap, and Vanguard Total Stock Market Index Fund ETF is trading nearer its 52-week high, Tempus AI nearer its low. Which is the better fit depends on your goals — on Pluang, investors hold Tempus AI for 22 Days and Vanguard Total Stock Market Index Fund ETF for 131 Days on average.
| TEM | VTI | |
|---|---|---|
Market Cap | $12.58B | $2.30T |
Volume | 7,444,569 | 2,982,924 |
Sector | Broad Market / Factor | — |
52-Week High | $99.28 | $384.30 |
52-Week Low | $41.55 | $311.68 |
Typical Hold Time | 22 Days | 131 Days |
Enterprise Value | $13.21B | — |
Signals from Pluang's Aura AI — not financial advice
Tempus AI (TEM) trades at $72.15, up 2.65% today, with a bullish technical signal and strong analyst support. The stock shows recent earnings beats but remains unprofitable, with a net income margin of -17.77% for 2026. Positive developments include FDA clearance for an AI product and expanded data partnerships, fueling investor optimism in the healthtech sector.
Outlook is cautiously optimistic given growth potential in AI-driven diagnostics, but high valuation (P/S 8.61) and persistent losses pose risks. Upside hinges on revenue scaling and path to profitability, with a consensus price target of $72.60 suggesting limited near-term gains from current levels.
VTI trades at $380.52, down slightly by 0.13% with a bullish technical signal from moving averages. The ETF maintains broad U.S. equity exposure across 3,500+ stocks, though concentration in top holdings remains significant. Recent news highlights long-term growth potential with $500 monthly investments since 2001 growing to approximately $876,000 according to Motley Fool (2026-10-01).
VTI offers diversified U.S. market access with low costs, suitable for long-term investors. Risks include market concentration in top holdings and broader economic sensitivity. Analyst sentiment remains positive for buy-and-hold strategies, though recent articles question the value added by small/mid-cap exposure versus S&P 500-focused alternatives.
Trailing returns across standard periods
What Pluang investors did over the last 30 days
Tempus AI Inc is a technology company. It has built the Tempus Platform, which comprises both a technology platform to free healthcare data from silos and an operating system to make the resulting data useful. Its Intelligent Diagnostics use AI, including generative AI, to make laboratory tests more accurate, tailored, and personal.
Read more on TEM →The fund employs an indexing investment approach designed to track the performance of the index, which represents approximately 100% of the investable US stock market and includes large-, mid-, small-, and micro-cap stocks. It invests by sampling the index, meaning that it holds a broadly diversified collection of securities that, in the aggregate, approximates the full index in terms of key characteristics.
Read more on VTI →