Tempus AI vs Upwork Inc — how do they compare? Tempus AI trades at $55.55 (market cap $9.93B), while Upwork Inc trades at $8.38 (market cap $1.22B). The key difference: Tempus AI is far larger — about 8.1× Upwork Inc's market cap, and Tempus AI is trading nearer its 52-week high, Upwork Inc nearer its low. Which is the better fit depends on your goals.
| TEM | UPWK | |
|---|---|---|
Market Cap | $9.93B | $1.22B |
Sector | Broad Market / Factor | Industrials |
52-Week High | $103.25 | $22.11 |
52-Week Low | $41.55 | $7.84 |
Enterprise Value | $10.56B | $1.02B |
Signals from Pluang's Aura AI — not financial advice
Tempus AI (TEM) trades at $52.05, up 12.86% in 24 hours, reflecting strong momentum after Q2 2026 earnings beat revenue estimates and raised 2026 sales guidance. The stock is technically bullish with moving averages supporting upside, while fundamentals show revenue growth to $1.4 billion in 2026 but persistent net losses. Recent news highlights expansion through the Personalis acquisition and AI-driven precision medicine advancements.
Outlook: Growth prospects are robust with AI adoption in healthcare and strategic deals, but high valuation ratios and negative profitability pose risks. Analysts are bullish with a $61.57 consensus target, though cash burn and competitive pressures require monitoring for sustained investor confidence.
UPWK trades at $9.67, up 2.65% today, with a bullish technical signal from moving averages and a neutral RSI. The company reported Q2 2026 revenue of $191.7 million, at the high end of guidance, and adjusted EBITDA of $64.1 million exceeding outlook, per MarketBeat on August 10, 2026. Valuation ratios appear reasonable with a P/E of 11.93 and P/S of 1.7, while profitability remains strong with a net income margin of 13.81% in 2025.
The outlook is mixed; analyst consensus is 52% buy with no sell ratings, but recent earnings misses and legal investigations pose risks. Revenue growth has slowed to 2.9% year-over-year in 2025, and net cash flow turned negative, indicating potential headwinds. Investors should weigh solid fundamentals against execution challenges and AI-driven market shifts.
Trailing returns across standard periods
Latest headlines on both assets
Tempus AI Inc is a technology company. It has built the Tempus Platform, which comprises both a technology platform to free healthcare data from silos and an operating system to make the resulting data useful. Its Intelligent Diagnostics use AI, including generative AI, to make laboratory tests more accurate, tailored, and personal.
Read more on TEM →Upwork Inc is a United States-based company that operates an online marketplace that enables businesses to find and work with highly-skilled independent professionals. The develops platform for hiring and freelancing purposes. Its products offering include Upwork Basic, Upwork Plus, Upwork Business, Upwork Enterprise, and Upwork Payroll. The business generates revenue from Talent and Clients across the USA, India, the Philippines and the rest of the world. Substantial income is derived from providing services to Clients.
Read more on UPWK →