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Compare Tempus AI (TEM) vs Twilio Inc (TWLO) Price & Performance

Twilio IncTrade

Price performance (Past 24H)

Key statistics

Tempus AI vs Twilio Inc — how do they compare? Tempus AI trades at $61.16 (market cap $11.67B), while Twilio Inc trades at $227.45 (market cap $34.69B). The key difference: Twilio Inc is far larger — about 3× Tempus AI's market cap, and Twilio Inc is trading nearer its 52-week high, Tempus AI nearer its low. Which is the better fit depends on your goals.

TEMTWLO
Market Cap
$11.67B$34.69B
Sector
Broad Market / FactorTechnology
52-Week High
$103.25$255.95
52-Week Low
$41.55$100.09
Enterprise Value
$12.30B$33.10B

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Tempus AI

Tempus AI (TEM) trades at $64.29, down 0.51% on the day, with a bullish technical signal and strong analyst support. The stock shows consistent earnings beats despite negative profitability, with a P/S of 7.99 and P/B of 26.23. Recent catalysts include FDA clearance for an AI ECG product and a $9.5 million ARPA-H award for autonomous AI in cardiology (Business Wire, September 9, 2026).

Outlook remains positive given analyst consensus and growth in precision medicine, but risks include sustained losses, high valuation multiples, and cash burn. The consensus price target is $69.11, implying potential upside, though investors must weigh the company's unprofitability against its innovation pipeline and market position.

Twilio Inc

Twilio (TWLO) trades at $225.89, down 3.04% today, showing strong fundamental momentum with three consecutive quarterly earnings beats and accelerating revenue growth from $3.8B in 2022 to $5.1B in 2025. The company has achieved profitability with a 20.62% net income margin in 2025, reversing previous losses, while technical indicators show a neutral stance with support at $222 and resistance at $230.

The outlook remains positive with 77% analyst buy ratings and a $266.31 consensus price target, representing 18% upside potential. Key risks include execution of AI strategy and competitive pressures in communications infrastructure, but strong free cash flow generation and strategic positioning for AI-driven customer engagement support the bullish case.

Returns comparison

Trailing returns across standard periods

About Tempus AI

Tempus AI Inc is a technology company. It has built the Tempus Platform, which comprises both a technology platform to free healthcare data from silos and an operating system to make the resulting data useful. Its Intelligent Diagnostics use AI, including generative AI, to make laboratory tests more accurate, tailored, and personal.

Read more on TEM

About Twilio Inc

Twilio Inc. is a cloud-based communication platform-as-a-service company offering communication building blocks that allow for a fully customized customer engagement experience spanning voice, video, chat, and SMS messaging. It does this through various application programming interfaces, or APIs, and prebuilt solution applications aimed at improving customer engagement. The company leverages its Super Network, a global network of carrier relationships, to facilitate high-speed, cost-effective communication.

Read more on TWLO