Crispr Therapeutics AG vs Palo Alto Networks Inc — how do they compare? Crispr Therapeutics AG trades at $50.54 (market cap $4.97B), while Palo Alto Networks Inc trades at $356.08 (market cap $287.61B). The key difference: Palo Alto Networks Inc is far larger — about 57.9× Crispr Therapeutics AG's market cap, and Palo Alto Networks Inc is trading nearer its 52-week high, Crispr Therapeutics AG nearer its low. Which is the better fit depends on your goals.
| CRSP | PANW | |
|---|---|---|
Market Cap | $4.97B | $287.61B |
Sector | Health | Technology |
52-Week High | $76.78 | $357.53 |
52-Week Low | $44.34 | $141.67 |
Enterprise Value | $3.32B | $286.57B |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
Palo Alto Networks (PANW) trades at $330.30, up 1.35% with a bullish technical outlook and strong earnings beats. The stock shows robust revenue growth to $9.22B in 2025 and a net income margin of 7.95%, though valuation ratios like P/E of 287.22 remain elevated. Recent news highlights cybersecurity sector tailwinds from AI-driven threats and IBM's client shifts, fueling positive sentiment.
Outlook is positive with 74% analyst buy ratings and a $336.65 consensus target, but high valuations and integration costs pose risks. Revenue growth and platformization strategy support upside, while competition and macroeconomic pressures require monitoring for sustained gains.
Trailing returns across standard periods
Latest headlines on both assets
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →Palo Alto Networks is a pure-play cybersecurity vendor that sells security appliances, subscriptions, and support into enterprises, government entities, and service providers. The company's product portfolio includes firewall appliances, virtual firewalls, endpoint protection, cloud security, and cybersecurity analytics. The Santa Clara, California, firm was established in 2005 and sells its products worldwide.
Read more on PANW →