Crispr Therapeutics AG vs Oracle Corporation — how do they compare? Crispr Therapeutics AG trades at $51.55 (market cap $4.97B), while Oracle Corporation trades at $132.95 (market cap $368.53B). The key difference: Oracle Corporation is far larger — about 74.2× Crispr Therapeutics AG's market cap, and Oracle Corporation pays a 1.56% dividend while Crispr Therapeutics AG pays none. Which is the better fit depends on your goals.
| CRSP | ORCL | |
|---|---|---|
Market Cap | $4.97B | $368.53B |
Sector | Health | Technology |
52-Week High | $76.78 | $328.33 |
52-Week Low | $44.34 | $127.96 |
Enterprise Value | $3.32B | $497.78B |
Dividend Yield | — | 1.56% |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
Oracle Corporation (ORCL) is trading at $127.96, down 2.96% in the last session, amid mixed technical signals with a bearish moving average trend but bullish oscillator readings. Fundamentally, the company shows strong profitability with 65.82% gross margins and 25.37% net income margins, supported by consistent earnings beats in recent quarters. Revenue growth has been steady, reaching $57.40B in 2025, with analyst consensus strongly favoring a Buy rating (65.12%) and a $259 price target representing significant upside potential.
The outlook for Oracle remains positive driven by AI infrastructure demand and strategic partnerships, though risks include high debt levels ($92.64B total debt) and competitive pressures in cloud services. Current valuation metrics (P/E 21.95, P/S 5.53) appear reasonable given growth prospects, but investors should monitor execution on AI initiatives and cash flow sustainability given substantial capital expenditures.
Trailing returns across standard periods
Latest headlines on both assets
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →Oracle provides database technology and enterprise resource planning, or ERP, software to enterprises around the world. Founded in 1977, Oracle pioneered the first commercial SQL-based relational database management system. Today, Oracle has 430,000 customers in 175 countries, supported by its base of 136,000 employees.
Read more on ORCL →