Crispr Therapeutics AG vs MasTec Inc — how do they compare? Crispr Therapeutics AG trades at $50.54 (market cap $4.97B), while MasTec Inc trades at $365.73 (market cap $28.85B). The key difference: MasTec Inc is far larger — about 5.8× Crispr Therapeutics AG's market cap, and MasTec Inc is trading nearer its 52-week high, Crispr Therapeutics AG nearer its low. Which is the better fit depends on your goals.
| CRSP | MTZ | |
|---|---|---|
Market Cap | $4.97B | $28.85B |
Sector | Health | Technology |
52-Week High | $76.78 | $437.51 |
52-Week Low | $44.34 | $171.92 |
Enterprise Value | $3.32B | $31.60B |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
MasTec (MTZ) trades at $360.21, down 3.4% on the day, with a bearish technical signal despite strong fundamental performance. The company recently announced a $1.65 billion acquisition of The Superior Group to expand its data center infrastructure capabilities, boosting its position in AI-driven markets. Recent quarterly earnings have consistently beaten expectations, with Q1 2026 showing 34% revenue growth and 73% adjusted EBITDA growth, supported by a record $20.3 billion backlog.
Wall Street maintains strong bullish sentiment with 89% buy ratings and a $481.77 consensus price target suggesting 34% upside potential. Key risks include integration challenges from the large acquisition and premium valuation metrics. The stock's current weakness presents a potential buying opportunity for investors bullish on infrastructure spending trends.
Trailing returns across standard periods
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →MasTec, Inc. is a leading infrastructure construction company operating mainly in North America. The company's services cover a diverse range of end-markets, including communications (building fiber and wireless infrastructure), oil & gas, electric power (transmission, distribution, and clean energy), and industrial projects. MTZ provides critical engineering, procurement, and construction (EPC) services that support the expansion and maintenance of essential infrastructure across the continent.
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