Crispr Therapeutics AG vs MasTec Inc — how do they compare? Crispr Therapeutics AG trades at $53.95 (market cap $5.23B), while MasTec Inc trades at $280.16 (market cap $21.90B). The key difference: MasTec Inc is far larger — about 4.2× Crispr Therapeutics AG's market cap, and MasTec Inc is trading nearer its 52-week high, Crispr Therapeutics AG nearer its low. Which is the better fit depends on your goals.
| CRSP | MTZ | |
|---|---|---|
Market Cap | $5.23B | $21.90B |
Sector | Health | Technology |
52-Week High | $76.78 | $437.51 |
52-Week Low | $44.34 | $172.51 |
Enterprise Value | $3.65B | $24.81B |
Signals from Pluang's Aura AI — not financial advice
CRISPR Therapeutics (CRSP) trades at $54.02, up 0.95% on the day, with strong technical momentum and bullish moving average signals. The company reported a Q2 2026 loss of $0.94 per share, beating estimates, while revenue growth is driven by CASGEVY sales expansion. Analyst sentiment remains positive with a $82.67 consensus price target representing 53% upside potential.
Despite promising pipeline developments and strong analyst support, CRSP faces significant fundamental challenges including negative profit margins, substantial cash burn, and high valuation multiples. The stock's near-term performance will depend on successful clinical trial outcomes and commercial execution of its gene-editing therapies.
MasTec (MTZ) trades at $281.11, up 4.78% over 24 hours, amid strong 2026 performance with record Q2 revenue of $4.37 billion and a $21.4 billion backlog. Technical indicators show a bearish trend with resistance near $283, while fundamentals reflect robust growth—40% EBITDA growth in Q2—though valuation multiples like a P/E of 43.42 suggest premium pricing. Recent news highlights the acquisition of The Superior Group and a $650 million senior notes offering, bolstering infrastructure capabilities.
The outlook is positive, driven by infrastructure demand and raised 2026 guidance, but risks include execution challenges from acquisitions and communications segment delays. Analysts are overwhelmingly bullish with an 88.89% buy rating and a $439.56 consensus target, implying significant upside from current levels.
Trailing returns across standard periods
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →MasTec, Inc. is a leading infrastructure construction company operating mainly in North America. The company's services cover a diverse range of end-markets, including communications (building fiber and wireless infrastructure), oil & gas, electric power (transmission, distribution, and clean energy), and industrial projects. MTZ provides critical engineering, procurement, and construction (EPC) services that support the expansion and maintenance of essential infrastructure across the continent.
Read more on MTZ →