Crispr Therapeutics AG vs Manhattan Associates Inc — how do they compare? Crispr Therapeutics AG trades at $50.54 (market cap $4.97B), while Manhattan Associates Inc trades at $157.9 (market cap $9.38B). The key difference: Manhattan Associates Inc is the larger of the two by market cap, and Manhattan Associates Inc is trading nearer its 52-week high, Crispr Therapeutics AG nearer its low. Which is the better fit depends on your goals.
| CRSP | MANH | |
|---|---|---|
Market Cap | $4.97B | $9.38B |
Sector | Health | Technology |
52-Week High | $76.78 | $227.94 |
52-Week Low | $44.34 | $120.88 |
Enterprise Value | $3.32B | $9.21B |
Signals from Pluang's Aura AI — not financial advice
CRSP trades at $50.63, down 5.1% over 24 hours, amid a bearish technical signal. The company shows deep losses with a net income margin of -56,853.4% in 2025 and negative cash flow from operations. However, analyst consensus remains optimistic with a $74.50 price target, and recent news highlights FDA approval for Casgevy, expanding its gene therapy market.
The outlook hinges on commercial execution of Casgevy and pipeline progress, offering high growth potential in gene editing. Key risks include sustained cash burn, competitive pressures, and regulatory hurdles. Despite current financial challenges, strong analyst buy ratings suggest confidence in long-term value.
MANH trades at $158.31, up 2.2% today, with a bullish technical outlook supported by moving averages and strong quarterly EPS beats. The company maintains robust profitability with a 19.68% net margin and 96.24% ROE, though valuation multiples like P/E of 44.43 are elevated. Recent news highlights ongoing legal investigations but also cloud growth initiatives.
Outlook remains positive with a $192.80 analyst price target implying 22% upside, but risks include high valuation sensitivity, legal overhang from fiduciary investigations, and competitive pressures in supply chain software. Earnings momentum and institutional support provide near-term catalysts.
Trailing returns across standard periods
Latest headlines on both assets
CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.
Read more on CRSP →Manhattan Associates, Inc. is a global leader in supply chain and omnichannel commerce software. The company provides a comprehensive suite of cloud-based and on-premise solutions for warehouse management (WMS), transportation management (TMS), and order management (OMS). MANH's technology helps retailers, wholesalers, and manufacturers manage inventory, optimize logistics, and unify the shopping experience across physical and digital channels.
Read more on MANH →