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Compare Crispr Therapeutics AG (CRSP) vs CSX Corporation (CSX) Price & Performance

Crispr Therapeutics AGTrade
CSX CorporationTrade

Price performance (Past 24H)

Key statistics

Crispr Therapeutics AG vs CSX Corporation — how do they compare? Crispr Therapeutics AG trades at $53.9 (market cap $5.23B), while CSX Corporation trades at $49.98 (market cap $92.55B). The key difference: CSX Corporation is far larger — about 17.7× Crispr Therapeutics AG's market cap, and CSX Corporation pays a 1.12% dividend while Crispr Therapeutics AG pays none. Which is the better fit depends on your goals.

CRSPCSX
Market Cap
$5.23B$92.55B
Sector
HealthIndustrials
52-Week High
$76.78$53.21
52-Week Low
$44.34$32.05
Enterprise Value
$3.65B$110.52B
Dividend Yield
1.12%

Aura AI Summary

Signals from Pluang's Aura AI — not financial advice

Crispr Therapeutics AG

CRISPR Therapeutics (CRSP) trades at $53.83, up 0.6% on the day, with a bullish technical signal from moving averages but overbought RSI readings. The company reported a Q2 2026 EPS beat with a loss of $0.94 versus an expected $1.19 loss, driven by surging CASGEVY sales. However, financials show deep losses, with a net income margin of -4,101.26% in 2025 and negative operating cash flow, though financing activities provided liquidity.

The outlook is mixed: strong analyst consensus (57.9% buy ratings) and a $82.67 price target reflect optimism around CASGEVY growth and pipeline catalysts, but high valuation (P/S of 466.05) and persistent cash burn pose significant risks. Investment appeal hinges on successful clinical advancements and path to profitability.

CSX Corporation

CSX trades at $50.08, down slightly by 0.09% today, with a neutral technical signal despite bullish moving averages. The railroad operator posted strong Q2 2026 results with EPS of $0.54 beating estimates by 4.2% and revenue growth of 10%, driving improved investor sentiment. Valuation metrics show a P/E of 29.05 and P/S of 6.41, while profitability remains solid with 22.21% net margins and 24.37% ROE. Recent news highlights volume growth and margin expansion as key catalysts.

CSX demonstrates operational strength with consecutive earnings beats and raised 2026 guidance, supported by intermodal demand and cost controls. However, declining revenue trends from $14.9B in 2022 to $14.1B in 2025 and high debt levels pose risks. Analyst consensus is bullish with a $52.57 price target (4.9% upside), though competitive pressures and fuel costs require monitoring for sustained growth.

Returns comparison

Trailing returns across standard periods

About Crispr Therapeutics AG

CRISPR Therapeutics is a gene editing company focused on the development of CRISPR/Cas9-based therapeutics. CRISPR/Cas9 stands for Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9), which is a revolutionary technology for precisely altering specific sequences of genomic DNA. The company is focused on using this technology to treat genetically defined diseases. CRISPR's most advanced pipeline candidate, CTX001, is in collaboration with Vertex Pharmaceuticals and targets sickle cell disease and transfusion-dependent beta-thalassemia, which have high unmet medical needs. The company is progressing additional gene editing programs for immuno-oncology, as well as a stem cell-derived therapy for the treatment of Type 1 diabetes.

Read more on CRSP

About CSX Corporation

Operating in the Eastern United States, Class I railroad CSX generated revenue near $12.5 billion in 2021. On its more than 21,000 miles of track, CSX hauls shipments of coal (13% of consolidated revenue), chemicals (22%), intermodal containers (16%), automotive cargo (9%), and a diverse mix of other bulk and industrial merchandise.

Read more on CSX