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Xilio Therapeutics doses first patient in Phase 1/2 trial of cancer drug XTX501 for metastatic NSCLC

Market News
26 Oct 2026, 14:30 WIB
GlobeNewsWire
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Bullish
Xilio Therapeutics doses first patient in Phase 1/2 trial of cancer drug XTX501 for metastatic NSCLC

Xilio Therapeutics has dosed the first patient in its Phase 1/2 clinical trial of XTX501, a novel bispecific antibody targeting PD-1 and masked IL-2, in metastatic non-small cell lung cancer (NSCLC) patients previously treated with anti-PD(L)-1 therapy. XTX501 aims to improve immune response by combining tumor-selective IL-2 activation with PD-1 inhibition, potentially offering a new backbone immunotherapy with fewer side effects. Initial Phase 1 data is expected in Q4 2027, and Xilio will present trial details at the upcoming Society for Immunotherapy of Cancer meeting.

Xilio Therapeutics' clinical trial news provides context for readers following health innovation. For readers following health-sector stocks, here is Pluang's market snapshot as of Oct 26, 2026 18:11 WIB: out of 150 priced stocks, 82 rose and 35 fell. Johnson & Johnson traded at USD 266.99 with a 1-day change of +1.21%, Immunovant Inc. was at USD 28.03 with a -1.34% change, and Tango Therapeutics Inc. stood at USD 23.61 with a +1.16% change.

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