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Hoth ends Phase 2a trial early on positive results, plans FDA talks for Phase 3 of cancer skin toxicity drug HT-001

Company Fundamentals
03 Nov 2026, 15:17 WIB
PRNewsWire
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Bullish
Hoth ends Phase 2a trial early on positive results, plans FDA talks for Phase 3 of cancer skin toxicity drug HT-001

Hoth Therapeutics, a subsidiary of Rocket One, has halted its Phase 2a trial of HT-001 early due to strong interim efficacy results in treating skin toxicity from cancer therapies. The company will seek FDA guidance to advance HT-001 into a potential Phase 3 trial, aiming to improve patient quality of life by managing side effects of EGFR inhibitor cancer treatments. This topical drug targets skin issues that often disrupt cancer therapy. Next steps depend on regulatory feedback and further data analysis.

HT-001's strong Phase 2a efficacy results are notable alongside Pluang's Health-sector snapshot. For readers following health stocks, here is Pluang's market snapshot as of Nov 03, 2026 20:11 WIB: Of 150 priced US Health-sector stocks, 75 rose and 69 fell. Vertex Pharmaceuticals (VRTX) traded at USD 565.98 with a 1-day change of +2.32% and a typical hold time of 123 days, with Pluang order activity showing 25% Sell and 75% Buy. Twist Bioscience (TWST) was priced at USD 131.82, up 2.15%, with a 27-day hold time and 18% Sell / 82% Buy activity. Amneal Pharmaceuticals (AMRX) closed at USD 20.00, down 2.15%, with a 12-day hold time and 0% Sell / 100% Buy activity.

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