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Parabilis reports 72.2% response rate for zolucatetide in desmoid tumors, advancing to Phase 3 trial in 2027.

Company Fundamentals
24 Oct 2026
GlobeNewsWire
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Bullish
Parabilis reports 72.2% response rate for zolucatetide in desmoid tumors, advancing to Phase 3 trial in 2027.

Parabilis Medicines announced updated Phase 1/2 trial data for zolucatetide, showing a 72.2% objective response rate and 100% disease control in patients with desmoid tumors at doses ≥450 mg. The drug demonstrated strong efficacy and a favorable safety profile, with no disease progression or treatment discontinuations due to adverse events. The FDA has aligned with the proposed dose and trial design, allowing Parabilis to initiate the Phase 3 PEDESTAL trial in early 2027, with results expected in 2029. This advancement offers hope for a new treatment targeting a previously undruggable pathway in desmoid tumors, a rare and challenging disease.

Parabilis Medicines' updated Phase 1/2 data for zolucatetide offers context for readers tracking health sector developments. For readers following health-sector stocks, here is Pluang's market snapshot as of Oct 24, 2026 18:11 WIB: out of 150 priced US health stocks, 44 rose and 105 fell. Notable movers include TNGX at USD 23.34 with a -16.43% change and 87% sell orders, WGS at USD 56.15 with a -16.37% change and balanced buy/sell activity, and CTXR at USD 0.40 with an +8.79% change and 98% buy orders. Typical hold times range from 1 to 20 days.

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