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Palisade Bio doses first patient in Phase 2b trial of oral ulcerative colitis drug PALI-2108

Market News
28 Oct 2026, 15:32 WIB
GlobeNewsWire
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Bullish
Palisade Bio doses first patient in Phase 2b trial of oral ulcerative colitis drug PALI-2108

Palisade Bio has dosed the first patient in its global Phase 2b ASCENTRA-UC trial testing PALI-2108, a once-daily oral drug for moderate to severe ulcerative colitis. The trial will enroll about 204 patients across approximately 115 sites worldwide, with topline results expected in Q4 2027. PALI-2108 is designed to target inflammation in the gut with potentially improved tolerability compared to similar drugs. Positive early Phase 1 results showed clinical response and remission in a small patient group, supporting further development.

Palisade Bio's Phase 2b ASCENTRA-UC trial has begun dosing patients, aiming to enroll about 204 participants globally. For readers following the health sector, here is Pluang's market snapshot as of Oct 28, 2026 19:11 WIB: out of 150 priced US health stocks, 42 rose and 97 fell. Notable movers include AXGN at USD 43.65 with a 16.52% increase and 100% sell order activity, NUWE at USD 4.71 down 13.42% with 100% sell orders, and BSX at USD 39.07 down 13.29% with 99% sell orders and a typical hold time of 81 days.

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