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Enozertinib shows strong results in first-line NSCLC with EGFR atypical mutations, advancing to global Phase 3 trial in 2027

Market News
23 Oct 2026
GlobeNewsWire
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Bullish
Enozertinib shows strong results in first-line NSCLC with EGFR atypical mutations, advancing to global Phase 3 trial in 2027

ORIC Pharmaceuticals announced promising Phase 1b data for enozertinib in first-line NSCLC patients with EGFR atypical mutations, showing an 84% systemic response rate and 70% intracranial response rate despite high baseline brain metastases. The drug demonstrated a favorable safety profile with no treatment-related discontinuations. Supported by these results and FDA interactions, ORIC plans to start a global Phase 3 trial, Redwood-1, in the first half of 2027, aiming to enroll around 360 patients. This advancement positions ORIC as a late-stage oncology company with significant commercial potential in lung and prostate cancers.

ORIC Pharmaceuticals' enozertinib shows promising Phase 1b data in NSCLC patients with EGFR atypical mutations. For readers following the Health sector, here is Pluang's market snapshot as of Oct 23, 2026 14:31 WIB: out of 150 priced Health-sector US stocks, 63 rose and 85 fell. Notable movers include GMED at USD 81.57 (+3.67%), NTRA at USD 398.34 (-3.64%), and TNGX at USD 27.91 (+3.45%) with 100% buy order activity on Pluang and a typical hold time of 2 days.

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