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Sofetabart mipitecan plus bevacizumab shows 79% response rate in platinum-sensitive ovarian cancer Phase 1 trial

Company Fundamentals
24 Oct 2026
PRNewsWire
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Bullish
Sofetabart mipitecan plus bevacizumab shows 79% response rate in platinum-sensitive ovarian cancer Phase 1 trial

Eli Lilly's investigational drug sofetabart mipitecan (Sofe-M), combined with bevacizumab, achieved a 79% confirmed objective response rate and 100% disease control rate in a Phase 1 study involving platinum-sensitive ovarian cancer patients. The treatment showed consistent effectiveness regardless of folate receptor alpha expression levels or prior PARP inhibitor exposure, a group typically with poor outcomes. Sofe-M is currently being evaluated in multiple Phase 3 trials under the FRAmework-01 program for both platinum-sensitive and platinum-resistant ovarian cancer. These results suggest a promising new treatment option for ovarian cancer patients with limited alternatives.

Following Eli Lilly's promising clinical data announcement for its ovarian cancer drug Sofe-M, the company's stock on Pluang is trading at USD 1,273.46 as of Oct 24, 2026 13:41 WIB. Despite the positive news, LLY shares have seen a 2.54% decline in the past day, with a market cap of $1.16 trillion. Investor activity on Pluang shows a majority leaning towards selling, with 76% of orders as of the same time.

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