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Iovance reports 24.6% response rate in lung cancer trial, plans precision TIL strategy for 2027 approval

Company Fundamentals
29 Oct 2026, 14:00 WIB
GlobeNewsWire
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Bullish
Iovance reports 24.6% response rate in lung cancer trial, plans precision TIL strategy for 2027 approval

Iovance Biotherapeutics updated results from its Phase 2 IOV-LUN-202 trial showing a 24.6% objective response rate in 69 patients with non-squamous metastatic non-small-cell lung cancer (mNSCLC). A biomarker-enriched subgroup with KRAS wild-type tumors showed a higher 59.1% response rate, guiding a new precision tumor infiltrating lymphocyte (TIL) therapy strategy. Enrollment is completing for cohorts supporting a supplemental biologics license application planned for 2027. Iovance will start a biomarker-enriched study, POSITILITY, in November 2026 to further evaluate this targeted approach.

Iovance Biotherapeutics has a market cap of $6.72 billion and an enterprise value of $6.65 billion as of October 29, 2026, 18:11 WIB. On Pluang, its stock price is USD 13.40, down 9.52% for the day with a volume of 8,779,721 shares traded. The platform shows a strong sell sentiment with 100% of order activity being sell orders, reflecting cautious investor behavior at this time.

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