The SAFFRON Phase III trial showed that combining ORPATHYS (savolitinib) with TAGRISSO (osimertinib) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with MET-driven EGFR-mutated non-small cell lung cancer (NSCLC) who had progressed on TAGRISSO alone. The combination reduced the risk of disease progression or death by 45% and extended median overall survival by nearly 5 months compared to chemotherapy. These results, presented at ESMO 2026 and published in The New England Journal of Medicine, establish this all-oral targeted therapy as a new standard for treating MET-driven resistance after EGFR TKI therapy. Regulatory submissions are underway in the US, Europe, and Japan, potentially expanding treatment options globally.
The HUTCHMED SAFFRON Phase III trial data is the subject, with Pluang's Health sector market context provided for readers. As of Oct 26, 2026 07:11 WIB, among 150 priced Health-sector US stocks on Pluang, 70 rose and 78 fell. Notable movers include AMLX at USD 27.20 with a -6.30% change and a typical hold time of 16 days, TWST at USD 139.84 down 6.23%, and NUVB at USD 4.57 down 5.77%.
Remittix is starting a test of its Earn platform, offering 100 participants weekly payouts with targeted yields of 18-22% APY on ETH, USDT, and USDC deposits, plus matching RTX token gifts. This move expands Remittix's PayFi ecosystem, which connects...
OpenWorld, Inc. announced it will dual list its shares on Nasdaq and the blockchain-based Figure OPEN platform by Q4 2026 after stockholders approved a new class of Blockchain Common Stock. This move allows investors to trade OpenWorld shares either ...
Ether (ETH) long positions totaling $11.52 million were liquidated on Binance, Bybit, and OKX within an hour ending 7:51 p.m. ET on Oct. 25, coinciding with a 1.12% drop in ETH price from $2,345 to $2,319. Short liquidations were much smaller, at $25...
Bitcoin's price fell below the $80,000 mark, reaching $79,900 as of 7:51 p.m. ET on October 25, according to Binance spot market data. This represents a 0.76% drop over the prior hour, with the price declining from $80,308 just 15 minutes earlier. Th...
Bitcoin (BTC) briefly rose above the $80,000 mark on Binance's spot market, reaching $80,014 at 7:46 p.m. ET on Sunday. This represented a small gain of about 0.11% in the last 15 minutes compared to $79,930 recorded earlier. Despite this short-term ...
