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Darolutamide with ADT and radiation cuts metastasis or death risk by 58% in high-risk prostate cancer patients.

Company Fundamentals
24 Oct 2026
Orion Corporation
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Bullish
Darolutamide with ADT and radiation cuts metastasis or death risk by 58% in high-risk prostate cancer patients.

Interim results from the Phase 3 DASL-HiCaP trial show that adding darolutamide to standard androgen deprivation therapy (ADT) and radiation therapy reduces the risk of metastasis or death by 58% in prostate cancer patients at high risk of recurrence. The 4-year metastasis-free survival rate was 95% with darolutamide versus 88% with placebo. Secondary endpoints also improved, and the safety profile was consistent with previous studies. These findings, presented at the ESMO Congress 2026, suggest darolutamide could become an important addition to early prostate cancer treatment, with ongoing follow-up to assess long-term survival outcomes.

Darolutamide's impact on prostate cancer patients at high risk of recurrence is highlighted by a 58% reduction in the risk of metastasis or death. For readers following the health sector, here is Pluang's market snapshot as of Oct 24, 2026 13:41 WIB: out of 150 priced US health stocks, 44 rose and 105 fell. Notable movers include LQDA at USD 42.65 (+7.46%, typical hold time 2 days, 56% buy orders), OSCR at USD 30.99 (-6.99%, typical hold time 16 days, 58% sell orders), and INO at USD 0.90 (+6.94%, typical hold time 43 days, 51% sell orders).

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