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CSL and Alentis partner to co-develop kidney and liver drug lixudebart with $355M upfront and $1.2B milestones

Company Fundamentals
04 Oct 2026
PRNewsWire
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Bullish
CSL and Alentis partner to co-develop kidney and liver drug lixudebart with $355M upfront and $1.2B milestones

CSL and Alentis Therapeutics have formed an exclusive global partnership to co-develop and co-promote lixudebart, a novel therapy targeting claudin-1 for kidney and liver diseases. CSL will pay Alentis $355 million upfront and up to $1.2 billion in milestones, sharing global profits 55% to CSL and 45% to Alentis. Lixudebart is in Phase 2 trials for ANCA-associated vasculitis with rapidly progressive glomerulonephritis (AAV-RPGN) and will also be developed for focal segmental glomerulosclerosis and primary sclerosing cholangitis. CSL will fund ongoing and planned trials, aiming to bring a first-in-class treatment to patients with rare, serious diseases affecting kidney and liver function.

The CSL and Alentis global partnership news comes as 49 of 100 Health-sector US stocks tradable on Pluang rose while 48 fell today. For readers following Health-sector stocks, here is Pluang's market snapshot as of Oct 05, 2026 04:51 WIB: TXG (10X Genomics Inc) rose 5.34% to USD 93.50 with a typical hold time of 93 days, ALNY (Alnylam Pharmaceuticals, Inc.) fell 4.96% to USD 219.72 with a typical hold time of 41 days, and CLPT (ClearPoint Neuro Inc) dropped 4.85% to USD 10.89 with a typical hold time of 9 days.

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