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Phase 3 trial shows dazodalibep improves systemic activity and dryness in Sjögren's disease patients

Market News
27 Oct 2026, 23:00 WIB
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Bullish
Phase 3 trial shows dazodalibep improves systemic activity and dryness in Sjögren's disease patients

Amgen announced positive Phase 3 OASIZ-301 trial results for dazodalibep, a CD40L antagonist, showing significant and meaningful reductions in systemic disease activity and patient-reported dryness in adults with moderate-to-severe Sjögren's disease. The drug demonstrated improvements as early as four weeks and was well tolerated with similar adverse event rates to placebo. These findings address a critical unmet need, as there are currently no FDA-approved treatments for Sjögren's disease. Amgen will also present additional data on other rare autoimmune disease treatments at ACR Convergence 2026, highlighting its commitment to rare diseases.

Amgen's stock price rose by 1.81% to USD 452.70 as of Oct 28, 2026 03:11 WIB on Pluang. The company's market capitalization stands at $240.38 billion, reflecting its significant presence in the health sector. Despite positive trial results, current Pluang order activity shows 100% sell interest in AMGN shares at this time.

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