Compare Vertex Pharmaceuticals Incorporated (VRTX) vs Zscaler Inc (ZS) Price & Performance
Price performance (Past 24H)
Key statistics
Key statistics
Vertex Pharmaceuticals Incorporated vs Zscaler Inc — how do they compare? Vertex Pharmaceuticals Incorporated trades at $522.29 (market cap $134.06B), while Zscaler Inc trades at $166.66 (market cap $26.41B). The key difference: Vertex Pharmaceuticals Incorporated is far larger — about 5.1× Zscaler Inc's market cap, and Vertex Pharmaceuticals Incorporated is trading nearer its 52-week high, Zscaler Inc nearer its low. Which is the better fit depends on your goals.
| VRTX | ZS | |
|---|---|---|
Market Cap | $134.06B | $26.41B |
Sector | Health | Technology |
52-Week High | $557.96 | $336.27 |
52-Week Low | $376.62 | $118.05 |
Enterprise Value | $128.18B | $24.79B |
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Aura AI Summary
Signals from Pluang's Aura AI — not financial advice
Vertex Pharmaceuticals (VRTX) trades at $528.9, down 3.15% on the day, amid a mixed technical and fundamental backdrop. The stock shows a bullish moving average signal but neutral oscillators, with key support at $522. Fundamentally, 2025 revenue reached $12.0B with a strong net income margin of 35%, though recent quarterly EPS results have been mixed. The company recently completed the acquisition of Crinetics Pharmaceuticals, signaling growth ambitions.
The outlook remains positive given analyst consensus favoring a Buy rating (84%) and a $548.78 price target, implying upside. Key opportunities include revenue growth from new drug launches, while risks involve competitive pressures and earnings volatility. The stock's current valuation at a P/E of 30.8 requires sustained execution to justify further gains.
Zscaler (ZS) trades at $161.94, down 4.63% amid bearish technical signals despite strong quarterly earnings beats. The stock shows improving fundamentals with revenue growing from $1.1B in 2022 to $2.67B in 2025, though net margins remain negative. Recent news highlights Zscaler's AI security innovations and conference presentations, while analyst consensus remains strongly bullish with a $204.88 price target representing 26% upside potential.
Zscaler presents a compelling growth story with accelerating revenue and strong enterprise adoption, though profitability challenges and elevated valuation metrics warrant caution. The stock's current weakness near support levels offers potential entry points for investors bullish on cybersecurity demand, particularly given Zscaler's leadership in zero-trust security and AI-driven threat protection capabilities.
Returns comparison
Trailing returns across standard periods
Returns comparison
Trailing returns across standard periods
Top news
Latest headlines on both assets
Top news
Latest headlines on both assets
About Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio for cystic fibrosis, where Vertex therapies remain the standard of care globally. In addition to its focus on cystic fibrosis, Vertex is diversifying its pipeline through gene-editing therapies such as CTX001 for beta-thalassemia and sickle-cell disease, small-molecule inhibitors targeting acute and chronic pain using non-opioid treatments, and small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
Read more on VRTX →About Zscaler Inc
Zscaler is a security-as-a-service firm that offers its customers cloud-delivered solutions for protecting user devices and data. The firm leverages its position in 150 colocation data centers to deliver traditionally appliance-based security functionality, such as firewalls and sandboxes, as a completely cloud-native platform. The firm focuses on large enterprise customers and offers two primary product suites: Zscaler Internet Access, which securely connects users to externally managed application and websites (such as Salesforce and Google), and Zscaler Private Access, which securely connects users to internally managed applications. Both product suites encompass a broad gamut of capabilities situated across the traditional security stack.
Read more on ZS →
